History of Military Contributions to the Creation of Vaccine-Serum Preparations Against Anthrax

Vaccination in combination with chemotherapeutic agents play an important role the complex of measures aimed at combating anthrax. However, Russian military scientists development means and methods specific biological protection against anthrax is not fully covered scientific literature. The aim article to summarize contribution creation vaccine-serum preparations In 1940–1980s branches Federal State Budgetary Establishment «48 Central Research Institute» Ministry Defence Federation, live combined vaccines have been created. Currently, these are located cities Kirov Yekaterinburg. 1998, researchers obtained a vaccine strain STI-PR-4 resistant number antibiotics. On basis this strain, dry was developed, which can be used foci infection together main drugs. 1996–1998 specialists branch (Kirov), Oryol biofactory, created new production line for heterologous (horse) anti-anthrax immunoglobulin, emergency pathogen. improvement drug completed by laboratory technology obtaining F(ab') 2 fragments, prophylaxis treatment task developing human immunoglobulin intravenous administration successfully solved 2004 (Kirov) Institution «Kirov Institute Hematology Blood Transfusion Roszdrav» within framework Target Program. 2020, employees developed mass immunization method using oral vaccine. ongoing advanced research on preparations, technologies their production, vaccination serious base, will make it possible future protect population personnel Armed Forces our country from outbreaks acts terrorism